Regulation and function of insulin-like growth factor-binding protein-1.

Abstract

Insulin-like growth factor-binding protein (IGFBP)-1 is one of six homologous proteins that specifically bind and modulate the mitogenic and metabolic actions of insulin-like growth factor (IGF)-I and IGF-II. Of the six IGFBP, IGFBP-1 is the only one that displays rapid dynamic regulation in vivo, with serum levels varying 10-fold or more in relation to… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.