Regulation and function of Zip4, the acrodermatitis enteropathica gene.

@article{Andrews2008RegulationAF,
  title={Regulation and function of Zip4, the acrodermatitis enteropathica gene.},
  author={G. K. Andrews},
  journal={Biochemical Society transactions},
  year={2008},
  volume={36 Pt 6},
  pages={1242-6}
}
The SLC39A (solute carrier 39A) [ZIP (Zrt-Irt-like protein)] family consists of 14 members which are thought to control zinc uptake into the cytoplasm. Among these, ZIP4 is known to be particularly important for zinc homoeostasis. Mutations in this gene cause acrodermatitis enteropathica, a rare recessive-lethal human genetic disorder. In the present paper… CONTINUE READING