Regulation and butanol inhibition of D-xylose and D-glucose uptake in Clostridium acetobutylicum.

  title={Regulation and butanol inhibition of D-xylose and D-glucose uptake in Clostridium acetobutylicum.},
  author={K Ounine and Henri Petitdemange and Guy Raval and R W Gay},
  journal={Applied and environmental microbiology},
  volume={49 4},
Clostridium acetobutylicum exhibited diauxie growth in the presence of mixtures of glucose and xylose. Both glucose- and xylose-grown cells had a glucose uptake activity. On the other hand, growth on xylose was associated with the induction of a xylose permease activity, which was repressed by glucose in xylose-induced cells. The rate of sugar uptake with increasing sugar concentrations showed saturation kinetics with an apparent Km of 1.25 X 10(-5) M for glucose and 5 X 10(-3) M for xylose… CONTINUE READING

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