Regulation and Biochemistry of Mouse Molybdo-flavoenzymes

@article{Vil2004RegulationAB,
  title={Regulation and Biochemistry of Mouse Molybdo-flavoenzymes},
  author={R. Vil{\`a} and M. Kurosaki and M. M. Barzago and M. Kolek and A. Bastone and L. Colombo and M. Salmona and M. Terao and E. Garattini},
  journal={Journal of Biological Chemistry},
  year={2004},
  volume={279},
  pages={8668 - 8683}
}
Mouse molybdo-flavoenzymes consist of xanthine oxidoreductase, aldehyde oxidase (AOX1), and two recently identified proteins, AOH1 and AOH2 (aldehyde oxidase homologues 1 and 2). Here we demonstrate that CD-1, C57BL/6, 129/Sv, and other mouse strains synthesize high levels of AOH1 in the liver and AOH2 in the skin. By contrast, the DBA/2 and CBA strains are unique, having a selective deficit in the expression of the AOH1 and AOH2 genes. DBA/2 animals synthesize trace amounts of a catalytically… Expand
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