Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach.


Described is the role that heat shock factor 1 (HSF1) plays in regulating cellular stress. Focusing on the current state of the HSF1 field in chemotherapeutics we outline the cytoprotective role of HSF1 in the cell. Summarizing the mechanism by which HSF1 regulates the unfolded proteins that are generated under stress conditions provides the background on… (More)
DOI: 10.1016/j.bmcl.2015.06.052


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Citations per Year

Citation Velocity: 8

Averaging 8 citations per year over the last 2 years.

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