Regulating the "size of mesh" in drug screening from statistical point of view demonstrated by a 2-step procedure of in vivo testing of antiviral compounds.

@article{Horn1977RegulatingT,
  title={Regulating the "size of mesh" in drug screening from statistical point of view demonstrated by a 2-step procedure of in vivo testing of antiviral compounds.},
  author={Martin Horn and Anneliese Veckenstedt and U Kanka},
  journal={Arzneimittel-Forschung},
  year={1977},
  volume={27 11},
  pages={2032-5}
}
The present paper indicates how to regulate the "size of mesh" in drug screening by sample size and/or by modification of the statistical procedure used. Such a regulation is demonstrated on a 2-step procedure of in vivo testing of antiviral compounds as an example, by changing the rules of decision with the parameter R0. From the computed probabilities of… CONTINUE READING