Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis.

Abstract

Fatty acid synthase (FAS) is a multifunctional homodimeric protein, and is the key enzyme required for the anabolic conversion of dietary carbohydrates to fatty acids. FAS synthesizes long-chain fatty acids from three substrates: acetyl-CoA as a primer, malonyl-CoA as a 2 carbon donor, and NADPH for reduction. The entire reaction is composed of numerous… (More)
DOI: 10.1016/j.bbalip.2015.12.002

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@article{Cui2016RegulatingEO, title={Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis.}, author={Wei Cui and Yan Liang and Weixi Tian and Mingjuan Ji and Xiaofeng Ma}, journal={Biochimica et biophysica acta}, year={2016}, volume={1861 3}, pages={149-55} }