Regulating Germ-Line Gene Therapy to avoid Sliding down the Slippery Slope

  title={Regulating Germ-Line Gene Therapy to avoid Sliding down the Slippery Slope},
  author={Shaun D Pattinson},
  journal={Medical Law International},
  pages={213 - 222}
  • S. Pattinson
  • Published 1 September 2000
  • Law
  • Medical Law International
Many arguments can be made for or against various regulatory approaches towards germ-line gene therapy and its associated research. A popular conclusion is that it ought to be prohibited, and this is commonly defended by use of a slippery slope argument. This paper will begin by outlining the regulatory approaches adopted towards germ-line gene therapy in EU countries, demonstrating the popularity of the restrictive approach. The slippery slope argument will then be examined. A number of… 

Ethical Challenges of Germline Genetic Enhancement

A series of concepts from the ethics and philosophy fields which are frequently used in studies that evaluate the ethical implications of germline genetic enhancement, such as dignity, benefit, autonomy, and identity are illustrated.

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A critical appraisal of the recent literature sets out the different models that are currently being investigated to bridge from studies in cell lines through towards clinical reality, and aims for the safe development of clinically effective delivery systems for DNA and RNAi technologies.

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The Clinical Progress of Gene Therapy and Its Ethical Standing



Human gene therapy and slippery slope arguments.

The author examines the topography of two different types of slippery slope argument, the logical slippery slope and the rhetorical slippery slope, and concludes that because of their dependence on probabilities that cannot be empirical proven they should be largely disregarded in the much more important debate on moral line-drawing in gene therapy.

Human gene therapy: down the slippery slope?

This argument will address human gene therapy in terms of each of the three versions of the slippery slope argument, partly relying on slippery slope arguments against this practice that have already surfaced in the literature.

Human gene therapy: why draw a line?

  • W. Anderson
  • Psychology
    The Journal of medicine and philosophy
  • 1989
Legitimate concerns about the potential for misuse of gene transfer technology justify drawing a moral line that includes corrective germline therapy but excludes enhancement interventions in both somatic and germline contexts.

Can human genetic enhancement be prohibited?

  • W. Gardner
  • Medicine
    The Journal of medicine and philosophy
  • 1995
The ethical discussion of genetic enhancement is reframe, which is the use of genetic engineering to supply a characteristic that a parent might want in a child that does not involve the treatment or prevention of disease, to provide a new perspective on slippery slopes to dangerous technology.

Is embryo research and preimplantation genetic diagnosis ethical?

Wrongful life actions as a means of regulating use of genetic and reproductive technologies.

The author would like to acknowledge the financial support provided by the British Academy, Arts and Hum anities Research Board.

Genetic disorders and the ethical status of germ-line gene therapy.

The first issue discussed here relates to making a distinction between negative and positive eugenics; the second issue deals with the evolutionary consequences of lost genetic diversity.

The Slippery Slope Argument

In public debates about the introduction of new technologies or about legalization of abortion, euthanasia, or HIV tests, an ever-recurrent argument is the slippery slope or wedge argument. It has

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