Regulated expression of CD36 during monocyte-to-macrophage differentiation: potential role of CD36 in foam cell formation.

@article{Huh1996RegulatedEO,
  title={Regulated expression of CD36 during monocyte-to-macrophage differentiation: potential role of CD36 in foam cell formation.},
  author={H Y Huh and S. Frieda A. Pearce and Lewis M. Yesner and Jon Schindler and Roy L Silverstein},
  journal={Blood},
  year={1996},
  volume={87 5},
  pages={2020-8}
}
CD36 is an 88-kD integral membrane glycoprotein expressed on monocytes, platelets, and certain microvascular endothelium serving distinct cellular functions both as an adhesive receptor for thrombospondin, collagen, and Plasmodium falciparum-infected erythrocytes, and as a scavenger receptor for oxidized low-density lipoprotein and apoptotic neutrophils. In this study, we examined the expression of CD36 during in vitro differentiation of peripheral blood monocytes into culture-derived… CONTINUE READING