Regular endurance training reduces the exercise induced HIF-1α and HIF-2α mRNA expression in human skeletal muscle in normoxic conditions

@article{Lundby2005RegularET,
  title={Regular endurance training reduces the exercise induced HIF-1α and HIF-2α mRNA expression in human skeletal muscle in normoxic conditions},
  author={Carsten Lundby and Max Gassmann and Henriette Pilegaard},
  journal={European Journal of Applied Physiology},
  year={2005},
  volume={96},
  pages={363-369}
}
Regular exercise induces a variety of adaptive responses that enhance the oxidative and metabolic capacity of human skeletal muscle. Although the physiological adjustments of regular exercise have been known for decades, the underlying mechanisms are still unclear. The hypoxia inducible factors 1 and 2 (HIFs) are clearly related heterodimeric transcription factors that consist of an oxygen-depended α-subunit and a constitutive β-subunit. With hypoxic exposure, HIF-1α and HIF-2α protein are… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

Muscle electrolytes in man

  • J Bergstrøm
  • Scan J Clin Lab Invest
  • 1962
Highly Influential
2 Excerpts

Similar Papers

Loading similar papers…