Regression of small-cell lung carcinoma in patients with paraneoplastic neuronal antibodies

@article{Darnell1993RegressionOS,
  title={Regression of small-cell lung carcinoma in patients with paraneoplastic neuronal antibodies},
  author={R. Darnell and L. Deangelis},
  journal={The Lancet},
  year={1993},
  volume={341},
  pages={21-22}
}
We describe three patients with known or suspected small-cell lung cancer (SCLC), paraneoplastic neurological syndromes, and antineuronal antibodies who had unusually benign clinical courses. One patient survived 8 years free of disease and was positive for the anti-Hu antibody. A second patient survived 6 years after spontaneous tumour regression and had an atypical antineuronal antibody. A third patient with both the anti-Hu and atypical antineuronal antibody had spontaneous regression of a… Expand
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Interventional Clinical Trial
This is an un-blinded Phase 1 study in which 21 patients suffering from solid advanced paediatric malignancies (14 sarcoma and 7 non-sarcoma patients) are treated with AV0113, an… Expand
ConditionsChildhood Solid Tumor
InterventionBiological, Other
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