Regression of left ventricular hypertrophy in experimental renovascular hypertension: diastolic dysfunction depends more on myocardial collagen than it does on myocardial mass.

@article{Dussaillant1996RegressionOL,
  title={Regression of left ventricular hypertrophy in experimental renovascular hypertension: diastolic dysfunction depends more on myocardial collagen than it does on myocardial mass.},
  author={Gast{\'o}n R Dussaillant and H{\'e}l{\`e}ne Gonzalez and Carlos Manuel de C{\'e}spedes and Jorge E. Jalil},
  journal={Journal of hypertension},
  year={1996},
  volume={14 9},
  pages={
          1117-23
        }
}
OBJECTIVE To evaluate regression of experimental left ventricular hypertrophy (LVH) in terms of its effects both on myocardial collagen levels and on diastolic stiffness. METHODS Two-kidney, one clip Goldblatt hypertensive rats were left untreated for 4 weeks (HT4W, n = 12) or 12 weeks (HT12W, n = 11) and compared with rats the treatment of which was started after 4 weeks of hypertension with 30 mg/kg per day losartan for 8 weeks (LOS, n = 12), or 50 mg/l enalapril for 8 weeks (ENA, n = 11… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-3 of 3 citations