Regression of Cardiac Rhabdomyomas in a Neonate after Everolimus Treatment

  title={Regression of Cardiac Rhabdomyomas in a Neonate after Everolimus Treatment},
  author={Helen Aghdasi Bornaun and Kazım {\"O}ztarhan and Tuğba Erener-Ercan and Reyhan Dedeoğlu and Deniz Tuğcu and Cigdem Yilmaz Aydogmus and Merih Çetinkaya and Sultan Kavuncuoğlu},
  booktitle={Case reports in pediatrics},
Cardiac rhabdomyoma often shows spontaneous regression and usually requires only close follow-up. However, patients with symptomatic inoperable rhabdomyomas may be candidates for everolimus treatment. Our patient had multiple inoperable cardiac rhabdomyomas causing serious left ventricle outflow-tract obstruction that showed a dramatic reduction in the size after everolimus therapy, a mammalian target of rapamycin (mTOR) inhibitor. After discontinuation of therapy, an increase in the diameter… CONTINUE READING

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