Regression and regrowth of tumour cords following single-dose anticancer treatment

@article{Bertuzzi2003RegressionAR,
  title={Regression and regrowth of tumour cords following single-dose anticancer treatment},
  author={Alessandro Bertuzzi and Alberto d'Onofrio and Antonio Fasano and Alberto Gandolfi},
  journal={Bulletin of Mathematical Biology},
  year={2003},
  volume={65},
  pages={903-931}
}
  • Alessandro Bertuzzi, Alberto d'Onofrio, +1 author Alberto Gandolfi
  • Published in
    Bulletin of mathematical…
    2003
  • Mathematics, Medicine
  • In this paper, the evolution of a tumour cord after treatment is investigated by extensive numerical simulations on the basis of a mathematical model developed by Bertuzzi et al. (submitted). The model is formulated in cylindrical symmetry adopting the continuum approach, and takes into account the influence of oxygen level on the proliferation and death rate of cells, the volume reduction due to disgregation of dead cells, and the cell killing effects of radiation and drugs. Some extensions of… CONTINUE READING

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