Regression Analysis of Combined Gene Expression Regulation in Acute Myeloid Leukemia

@inproceedings{Li2014RegressionAO,
  title={Regression Analysis of Combined Gene Expression Regulation in Acute Myeloid Leukemia},
  author={Yue Li and Minggao Liang and Zhaolei Zhang},
  booktitle={PLoS Computational Biology},
  year={2014}
}
Gene expression is a combinatorial function of genetic/epigenetic factors such as copy number variation (CNV), DNA methylation (DM), transcription factors (TF) occupancy, and microRNA (miRNA) post-transcriptional regulation. At the maturity of microarray/sequencing technologies, large amounts of data measuring the genome-wide signals of those factors became available from Encyclopedia of DNA Elements (ENCODE) and The Cancer Genome Atlas (TCGA). However, there is a lack of an integrative model… CONTINUE READING
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