Registration of longitudinal brain image sequences with implicit template and spatial-temporal heuristics

@article{Wu2012RegistrationOL,
  title={Registration of longitudinal brain image sequences with implicit template and spatial-temporal heuristics},
  author={Guorong Wu and Qian Wang and Dinggang Shen},
  journal={NeuroImage},
  year={2012},
  volume={59 1},
  pages={404-21}
}
Accurate measurement of longitudinal changes of brain structures and functions is very important but challenging in many clinical studies. Also, across-subject comparison of longitudinal changes is critical in identifying disease-related changes. In this paper, we propose a novel method to meet these two requirements by simultaneously registering sets of longitudinal image sequences of different subjects to the common space, without assuming any explicit template. Specifically, our goal is to 1… CONTINUE READING