Regioselective functionalization of alkanes by sequential dehydrogenation-hydrozirconation.
@article{Kuninobu2010RegioselectiveFO,
title={Regioselective functionalization of alkanes by sequential dehydrogenation-hydrozirconation.},
author={Yoichiro Kuninobu and Tomonari Ureshino and Shun Ichi Yamamoto and Kazuhiko Takai},
journal={Chemical communications},
year={2010},
volume={46 29},
pages={
5310-2
}
}We have succeeded in formal regioselective functionalization of alkanes by iridium-catalyzed dehydrogenation, hydrozirconation of the resulting alkenes, and electrophilic reaction of the generated alkylzirconium intermediate.
7 Citations
Regioselective Functionalization of Alkanes by Sequential Dehydrogenation—Hydrozirconation.
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The iridium-catalyzed dehydrogenation of alkanes followed by hydrozirconation of the resulting mixture of alkenes leads to isomerized 1-alkylzirconocene intermediates, which can be readily trapped by…
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Organozirconium chemistry has found extensive applications in organic synthesis since its discovery in the last century. Alkylzirconocenes, which are easily generated by the hydrozirconation of…
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It is shown that, unlike other more mature areas, the chemistry of polyhydrides offers new exciting conceptual challenges and at the same time the possibility of interacting with other fields including the conversion and storage of regenerative energy, organic synthetic chemistry, drug design, and material science.
References
SHOWING 1-10 OF 23 REFERENCES
Photochemical dehydrogenation of alkanes catalyzed by trans-carbonylchlorobis(trimethylphosphine)rhodium: Aspects of selectivity and mechanism
- Chemistry
- 1989
Deshydrogenation photochimique des methyl- et isopropyl cyclohexanes. Obtention d'alkyl cyclohexenes, de methylidene et d'isopropenyl cyclohexanes
Hydrozirconation: A New Transition Metal Reagent for Organic Synthesis
- Chemistry
- 1976
Hydrozirconation has recently been developed as a procedure for functionalizing alkenes, alkynes, and 1,3-dienes via organozirconium(IV) intermediates. These intermediates react with a variety of…
Highly Catalytic Dehydrogenation of Alkanes to Olefins via C–H Activation in the Presence of RhCl(CO)(PMe3)2 under Irradiation
- Chemistry
- 1988
Olefins and dihydrogen were catalytically formed from alkanes at an ambient temperature in the presence of RhCl (CO)(PMe3)2 under irradiation.
Efficient catalytic C–H activation of alkanes: regioselective carbonylation of the terminal methyl group of n-pentane by RhCl(CO)(PMe3)2
- Chemistry
- 1987
The terminal methyl group of n-pentane was regioselectively carbonylated to give n-hexanal under mild conditions (1 atm pressure of CO, room temperature) by photocatalysis in the presence of…
n-Alkene and dihydrogen formation from n-alkanes by photocatalysis using carbonyl(chloro)phosphine–rhodium complexes
- Chemistry
- 1988
n-Alkenes and dihydrogen were obtained from n-alkanes by photocatalysis using carbonyl(chloro)phosphine–rhodium complexes; the rate of alkane dehydrogenation was the same as that of propan-2-ol…
Thermal, catalytic, regiospecific functionalization of alkanes
- ChemistryScience
- 2000
The rhodium complex Cp*Rh(eta(4)-C(6)Me(6)) (Cp*, C(5)Me (5); Me, methyl) catalyzes the high-yield formation of linear alkylboranes from commercially available borane reagents under thermal conditions.
Functionalization of organic molecules by transition-metal-catalyzed C(sp3)-H activation.
- ChemistryChemistry
- 2010
This Minireview highlights recent work in transition-metal-catalyzed C-H activation, with a particular emphasis on synthetically useful methods for activation of non-acidic C- H bonds of alkyl groups.