Regioselective Synthesis ofHighly Functionalized 3-Spiropyrrolidine/pyrrolizidineOxindoles and Acenaphthenones via One-Pot Four-Component [3+2] Cycloaddition

@inproceedings{Zhao2010RegioselectiveSO,
  title={Regioselective Synthesis ofHighly Functionalized 3-Spiropyrrolidine/pyrrolizidineOxindoles and Acenaphthenones via One-Pot Four-Component [3+2] Cycloaddition},
  author={Kai Zhao and Songlei Zhu and Daqing Shi and Xiao-Ping Xu and Shun-Jun Ji},
  year={2010}
}
  • Kai Zhao, Songlei Zhu, +2 authors Shun-Jun Ji
  • Published 2010
  • Chemistry
  • A facile and efficient entry into highly functionalized 3-spiropyrrolidineoxindoles and 3-spiropyrrolizidine oxindoles, as well as to 3-spiropyrrolidineacenaphthenones via one-pot four-component reactions of 3-cyanoacetylindoles,aldehydes, isatin/acenaphthylene-1,2-dione and amino acidhas been developed. Particularly valuable features of this methodinclude high yields of products, broad substrate scope and a straightforwardprocedure. 

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