Regions, systems, and the brain: Hierarchical measures of functional integration in fMRI

  title={Regions, systems, and the brain: Hierarchical measures of functional integration in fMRI},
  author={Guillaume Marrelec and Pierre Bellec and Alexandre Krainik and Hugues Duffau and M{\'e}lanie P{\'e}l{\'e}grini-Issac and St{\'e}phane Leh{\'e}ricy and Habib Benali and Julien Doyon},
  journal={Medical image analysis},
  volume={12 4},
In neuroscience, the notion has emerged that the brain abides by two principles: segregation and integration. Segregation into functionally specialized systems and integration of information flow across systems are basic principles that are thought to shape the functional architecture of the brain. A measure called integration, originating from information theory and derived from mutual information, has been proposed to characterize the global integrative state of a network. In this paper, we… CONTINUE READING


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