Regional variations in the glial influence on synapse development in the mouse CNS.

@article{Steinmetz2006RegionalVI,
  title={Regional variations in the glial influence on synapse development in the mouse CNS.},
  author={Celine C Steinmetz and Isabelle Buard and Thomas Claudepierre and Karl N{\"a}gler and Frank W Pfrieger},
  journal={The Journal of physiology},
  year={2006},
  volume={577 Pt 1},
  pages={249-61}
}
There is increasing evidence that synapse function depends on interactions with glial cells, namely astrocytes. Studies on specific neurons of the central nervous system (CNS) indicated that glial signals also control synapse development, but it remained unclear whether this is a general principle that applies to other neuronal cell types. To address this question, we developed new methods to immunoisolate neurons from different brain regions of postnatal mice and to culture them in a… CONTINUE READING

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