Regional variations in intestinal brush border membrane fluidity and function during diabetes and the role of oxidative stress and non-enzymatic glycation

@article{Bhor2003RegionalVI,
  title={Regional variations in intestinal brush border membrane fluidity and function during diabetes and the role of oxidative stress and non-enzymatic glycation},
  author={V. M. Bhor and Subramanian Sivakami},
  journal={Molecular and Cellular Biochemistry},
  year={2003},
  volume={252},
  pages={125-132}
}
The physical state (fluidity) of lipids modulates the activities of several membrane bound enzymes and transport proteins. Alteration of brush border membrane (BBM) fluidity is one of the several changes exhibited by the small intestine during diabetes. In the present study, an investigation of the diabetes induced regional changes in fluidity, oxidative damage, non-enzymatic glycation as well as the activities and the kinetic parameters of the enzymes alkaline phosphatase and γ-glutamyl… CONTINUE READING
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