Regional variation in the guinea-pig virulence and other characteristics of tubercle bacilli


Pretreatment, isoniazid-sensitive cultures ofM. tuberculosis were obtained from 36 patients at each of 9 centres (Britain, Teheran, Afghan-Pakistan border, East Africa, Madras, Rangoon, Djakarta, Hong Kong). In the guinea-pig, the virulence of the cultures was uniformly high. The mean virulence of cultures was lower in East Africa, lower still in Madras… (More)
DOI: 10.1007/BF02095209

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