Regional variation in CCR5-Δ32 gene distribution among women from the US HIV Epidemiology Research Study (HERS)

@article{Downer2002RegionalVI,
  title={Regional variation in CCR5-Δ32 gene distribution among women from the US HIV Epidemiology Research Study (HERS)},
  author={Marie Downer and Thomas Hodge and Dawn K. Smith and Shoukat H. Qari and Paula Schuman and Kenneth H. Mayer and Robert S. Klein and David Vlahov and Lytt I. Gardner and Janet M. McNicholl},
  journal={Genes and Immunity},
  year={2002},
  volume={3},
  pages={295-298}
}
The CCR5-Δ32 genotype is known to influence HIV-1 transmission and disease. We genotyped 1301 US women of various races/ethnicities participating in the HIV Epidemiologic Research Study. None was homozygous for CCR5-Δ32. The distribution of heterozygotes was similar in HIV-1 infected and uninfected women. Thirty-seven (11.8%) white, 28 (3.7%) blacks/African Americans (AA), seven (3.3%) Hispanics/Latinas, and one (6.6%) other race/ethnicity were heterozygous. The frequency of heterozygotes… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 22 references

- free survival and slower CD 4 T - cell decline in a cohort of HIV - seropositive individuals

  • DK Smith, DL Warren, D Vlahov
  • 1997

Analysis of genetic polymorphism of the HIV-coreceptor (CCR5) locus in a Gabonese population (abstract 044A297)

  • C Lu, T Williams, M Makuwa
  • Presented at Xth International Conference on AIDS…
  • 1997

Similar Papers

Loading similar papers…