Regional treatment effects in studies of cardiorenal drugs: a summary of recent clinical trials.

@article{Lawrence2012RegionalTE,
  title={Regional treatment effects in studies of cardiorenal drugs: a summary of recent clinical trials.},
  author={John Lawrence and Steve Bai and H. M. James Hung and Robert O'Neill},
  journal={Journal of the American College of Cardiology},
  year={2012},
  volume={60 12},
  pages={1117-8}
}
To the Editor: The global treatment effect in a multinational trial design can be difficult to interpret when that global treatment effect does not reflect a consistent finding within the trial regional sites. This global treatment effect may not apply to the populations of each of the countries separately. The literature on the topic of differences in… CONTINUE READING

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