Regional replication of the bacterial chromosome induced by derepression of prophage lambda

@article{Fukasawa1970RegionalRO,
  title={Regional replication of the bacterial chromosome induced by derepression of prophage lambda},
  author={Toshio Fukasawa and Kanji Hirai and Takashi Segawa and K. Obonai},
  journal={Molecular and General Genetics MGG},
  year={1970},
  volume={147},
  pages={71-78}
}
Derepression of prophage λ in E. coli strain K12 results in constitutive synthesis of the enzymes directed by the nearby bacterial operon, gal (escape synthesis). Phage 82 fails to cause escape synthesis despite that it lysogenizes the strain K12 at the site identical to that of λ on the host chromosome. The reason for the observed difference between 82 and λ is studied in the light of the recent finding that escape synthesis in λ-lysogen is closely associated to phage-promoted replication of… CONTINUE READING
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