Regional quantification of white matter hyperintensity in normal aging, mild cognitive impairment, and Alzheimer's disease.

@article{Chen2006RegionalQO,
  title={Regional quantification of white matter hyperintensity in normal aging, mild cognitive impairment, and Alzheimer's disease.},
  author={Ya-Fang Chen and Huali Wang and Yong Chu and Y Huang and M F Su},
  journal={Dementia and geriatric cognitive disorders},
  year={2006},
  volume={22 2},
  pages={177-84}
}
BACKGROUND/AIMS A quantitative method was applied to measure the volume of white matter hyperintensity (WMH) in different brain regions of subjects with Alzheimer's disease (AD), mild cognitive impairment (MCI) and normal healthy age-matched controls, and the relationship between regional WMH and age and cognitive function was investigated. METHODS Fifty-six subjects were included in this study, 27 AD, 15 MCI and 14 normal age-matched controls. A user-friendly software was developed for WMH… CONTINUE READING
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