Regional proton magnetic resonance spectroscopy in schizophrenia and exploration of drug effect

@article{Heimberg1998RegionalPM,
  title={Regional proton magnetic resonance spectroscopy in schizophrenia and exploration of drug effect},
  author={Carolyn Heimberg and Richard A. Komoroski and William Lawson and David Cardwell and Craig N. Karson},
  journal={Psychiatry Research: Neuroimaging},
  year={1998},
  volume={83},
  pages={105-115}
}
Schizophrenia is a disorder with an unclear pathophysiology, despite numerous attempts to elucidate its etiology. We have employed proton magnetic resonance spectroscopy in vivo to explore the neurochemistry of several brain regions (left frontal and temporal cortices, left basal ganglia, and left and right thalamus) in patients with schizophrenia and in normal control subjects. We have also examined patients in different medication states. A trend toward a decreased level of inositol/creatine… CONTINUE READING

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