Regional myocardial flow and capillary permeability-surface area products are nearly proportional.

@article{Caldwell1994RegionalMF,
  title={Regional myocardial flow and capillary permeability-surface area products are nearly proportional.},
  author={James H. Caldwell and Gary V Martin and Gary M. Raymond and James B. Bassingthwaighte},
  journal={The American journal of physiology},
  year={1994},
  volume={267 2 Pt 2},
  pages={H654-66}
}
Analyses of data on the transcapillary exchange and cellular uptake in the normal heart have generally been based on the assumption that local membrane conductances and volumes of distribution are everywhere the same. The question is whether such an assumption is justified in view of the marked (sixfold) heterogeneity of local blood flows per gram tissue. The method was to estimate both flow and capillary membrane permeability-surface area products (PS) locally in the heart. For each of five… CONTINUE READING
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