Regional manifestations and control of the immune system.

  title={Regional manifestations and control of the immune system.},
  author={Soheyla Saadi and Lucile E. Wrenshall and Jeffey L Platt},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={16 8},
Although immune responses are generally considered to be systemic, local events such as interaction of complement products with blood vessels and with inflammatory cells play a pivotal role in determining the nature and manifestations of immune responses. This paper will discuss how blood vessel physiology and immunity influence one another to reach homeostasis upon exposure to an infectious agent. We review new insights into the mechanisms by which the microenvironment of tissues protects… CONTINUE READING

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