Regional localisation of two non-specific X-linked mental retardation genes (MRX30 and MRX31).

@article{Donnelly1996RegionalLO,
  title={Regional localisation of two non-specific X-linked mental retardation genes (MRX30 and MRX31).},
  author={Andrew James Donnelly and M. W. Partington and A K Ryan and John C. Mulley},
  journal={American journal of medical genetics},
  year={1996},
  volume={64 1},
  pages={
          113-20
        }
}
Two genes responsible for X-linked mental retardation have been localised by linkage analysis. MRX30 maps to a 28 cM region flanked by the loci DXS990 (Xq21.3) and DXS424 (Xq24). A significant multipoint lod score of 2.78 was detected between the loci DXS1120 and DXS456. MRX31 maps to a 12 cM region that spans the centromere from DXS1126 (Xp11.23) to DXS1124 (Xq13.3). Significant two-point lod scores, at a recombination fraction of zero, were obtained with the loci DXS991 (Zmax = 2.06), AR… CONTINUE READING

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