Regional haemodynamic changes during oral ingestion of NG-monomethyl-L-arginine or NG-nitro-L-arginine methyl ester in conscious Brattleboro rats.

@article{Gardiner1990RegionalHC,
  title={Regional haemodynamic changes during oral ingestion of NG-monomethyl-L-arginine or NG-nitro-L-arginine methyl ester in conscious Brattleboro rats.},
  author={Sheila M. Gardiner and A. M. Compton and Terence Bennett and Richard M J Palmer and Salvador Moncada},
  journal={British journal of pharmacology},
  year={1990},
  volume={101 1},
  pages={10-2}
}
Homozygous Brattleboro (i.e. vasopressin-deficient) rats were chronically instrumented with pulsed Doppler probes and intravascular catheters to permit continuous monitoring of regional haemodynamics. Over a 9 h period, rats drinking water showed no systematic changes in heart rate or mean arterial blood pressure although renal, mesenteric and hindquarters… CONTINUE READING