Regional gray matter volume abnormalities in the at risk mental state.

  title={Regional gray matter volume abnormalities in the at risk mental state.},
  author={Stefan J. Borgwardt and Anita Riecher-R{\"o}ssler and Paola Dazzan and Xavier Chitnis and Jacqueline Aston and Margret Drewe and Ute Gschwandtner and Sven Haller and Marlon O. Pflueger and Evelyne Rechsteiner and Marcus D'Souza and R. -D. Stieglitz and Ernst-Wilhelm Radue and Philip K. McGuire},
  journal={Biological psychiatry},
  volume={61 10},
BACKGROUND Individuals with an At Risk Mental State (ARMS) have a very high risk of developing a psychotic disorder but the basis of this risk is unclear. We addressed this issue by studying gray matter volume in this group with magnetic resonance imaging (MRI). METHODS Thirty-five individuals with an ARMS, 25 patients with first episode schizophrenia, and 22 healthy volunteers were studied using a 1.5T MRI scanner. Twelve (34%) of the ARMS group developed schizophrenia in the 2 years… CONTINUE READING
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