Regional expression of the homeobox gene NKX2-1 defines pallidal and interneuronal populations in the basal ganglia of amphibians.

@article{Gonzlez2002RegionalEO,
  title={Regional expression of the homeobox gene NKX2-1 defines pallidal and interneuronal populations in the basal ganglia of amphibians.},
  author={Agust{\'i}n Gonz{\'a}lez and Jes{\'u}s Mar{\'i}a L{\'o}pez and Cristina S{\'a}nchez-Camacho and Oscar Mar{\'i}n},
  journal={Neuroscience},
  year={2002},
  volume={114 3},
  pages={567-75}
}
The distribution of gene expression domains during development constitutes a novel tool for the identification of distinct brain regions. This is particularly useful in the brain of amphibians where cell migration is very limited and most neurons organize in a periventricular layer. Here we report the expression pattern of NKX2-1 protein in the developing Xenopus telencephalon. In mammals, the Nkx2-1 gene is expressed in distinct subpallial regions such as the septum, the medial ganglionic… CONTINUE READING
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