Regional distribution of neuropeptide Y Y2 receptor messenger RNA in the human post mortem brain

@article{Caberlotto1998RegionalDO,
  title={Regional distribution of neuropeptide Y Y2 receptor messenger RNA in the human post mortem brain},
  author={Laura Caberlotto and Kjell Fuxe and Joseph M. Rimland and G{\"o}ran Sedvall and Yasmin L. Hurd},
  journal={Neuroscience},
  year={1998},
  volume={86},
  pages={167-178}
}
Conservation of Expression of Neuropeptide Y5 Receptor between Human and Rat Hypothalamus and Limbic Regions Suggests an Integral Role in Central Neuroendocrine Control
TLDR
A detailed analysis of Y5 expression in rat brain using in situ hybridization histochemistry with digoxygenin-labeled riboprobes and compared this to expression of Y4 in human brain regions implies sharing of a major neuroendocrine functional role by this receptor.
Characterization of neuropeptide Y2 receptor protein expression in the mouse brain. I. Distribution in cell bodies and nerve terminals
TLDR
Y2R immunoreactivity was specific with its absence in Y2R knockout (KO) mice and in adjacent sections following preadsorption with the immunogenic peptide (10−5 M), and the widespread distribution of Y1, Y2, Y5, and y6 receptors suggests that NPY signaling through the Y2 R is common in the mouse brain.
Neuropeptide Y Y1 and Y2 Receptor mRNA Expression in the Prefrontal Cortex of Psychiatric Subjects
Plasticity of Y1 and Y2 Receptors and Neuropeptide Y Fibers in Patients with Temporal Lobe Epilepsy
TLDR
It is suggested that abundant sprouting of NPY fibers, concomitant upregulation of Y2 receptors, and down regulation of Y1 receptors in the hippocampus of patients with Ammon's horn sclerosis may be endogenous anticonvulsant mechanisms.
Review Distribution of NPY receptors in the hypothalamus
TLDR
The histochemical analyses allow characterization of coexisting molecules and in this way definition of the neurochemistry of NPY circuitries are defined by showing coexistence of various NPY receptors they provide a morphological basis for in vitro studies showing heterodimerization ofNPY receptors.
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TLDR
The results indicate that the Y1 receptor gene is abundant in the human brain and this receptor may have important roles in cognitive, limbic and motor function.
Regional Distribution of Putative NPY Y1 Receptors and Neurons Expressing Y1 mRNA in Forebrain Areas of the Rat Central Nervous System
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The present study further clarifies the anatomical distribution of multiple NPY binding sites within the central nervous system of the rat, and extends earlier suggestions that Y1 and Y2 receptor types are present within thecentral nervous system.
Comparative characterization and autoradiographic distribution of neuropeptide Y receptor subtypes in the rat brain
TLDR
The extensive characterization and visualization of at least two classes of NPY receptor sites using a highly selective Y1 analog, [Leu31, pro34]- NPY or [Pro34]-NPY, and a relatively specific Y2 competitor, NPY13-36 are reported on.
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