Regional distribution and production rate of 3-methoxy-4-hydroxyphenylethyleneglycol sulphate (MHPG-SO4) in rat brain.

@article{Kohno1981RegionalDA,
  title={Regional distribution and production rate of 3-methoxy-4-hydroxyphenylethyleneglycol sulphate (MHPG-SO4) in rat brain.},
  author={Yoshiro Kohno and Masatoshi Tanaka and Reiko Nakagawa and N Toshima and Nobuykuki Nagasaki},
  journal={Journal of neurochemistry},
  year={1981},
  volume={36 1},
  pages={286-9}
}
The levels of noradrenaline (NA) and 3-methoxy-4-hydroxyphenylethyleneglycol sulphate (MHPG-SO4) in 15 brain regions showed a parallel distribution in male Wistar rats. The differences in regional distribution of MHPG-SO4 were similar to those in the rate of NA turnover reported by other investigators. The accumulation rates of MHPG-SO4 during 45 and 90 min after probenecid injection significantly correlated to the steady state levels of MHPG-SO4 in nine regions studied. With the results, the… CONTINUE READING

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