Regional disposal of intravenously infused glucose during prolonged hyperglycemia-hyperinsulinemia.

@article{Sidossis1999RegionalDO,
  title={Regional disposal of intravenously infused glucose during prolonged hyperglycemia-hyperinsulinemia.},
  author={Labros S. Sidossis and Bettina Mittendorfer and Eric Walser and Robert R. Wolfe},
  journal={The Journal of nutritional biochemistry},
  year={1999},
  volume={10 9},
  pages={547-54}
}
We measured splanchnic and leg glucose uptake during prolonged (i.e., 15 hours), moderate hyperglycemia-hyperinsulinemia (clamp). Plasma free fatty acid (FFA) concentration was maintained at basal concentration during the clamp via infusion of exogenous lipids and heparin in healthy volunteers to create a metabolic profile similar to glucose intolerance (i… CONTINUE READING