Regional differences within the rat ventral tegmental area for muscimol self-infusions.

@article{Ikemoto1998RegionalDW,
  title={Regional differences within the rat ventral tegmental area for muscimol self-infusions.},
  author={Satoshi Ikemoto and James M Murphy and William J H Mcbride},
  journal={Pharmacology, biochemistry, and behavior},
  year={1998},
  volume={61 1},
  pages={87-92}
}
The present study examined the effects of activating GABA(A) receptors in the anterior and posterior regions of the ventral tegmental area (VTA) on operant reinforcement behavior, using the technique of intracranial self-administration. Rats were given the opportunity to self-administer vehicle alone (artificial CSF) and vehicle containing 25, 50, and 100 microM muscimol, a GABA(A) agonist, into the anterior or posterior VTA during four sessions (3 h/session) in standard two-lever operant… CONTINUE READING

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