Regional differences in the expression of K+–Cl− 2 cotransporter in the developing rat cortex

Abstract

The type 2 potassium–chloride cotransporter (KCC2) is the main regulator of intracellular chloride concentration in CNS neurons, and plays a crucial role in spine development that is independent of its ion cotransport function. The expression pattern of KCC2 is upregulated during postnatal development showing area and layer-specific differences in distinct… (More)
DOI: 10.1007/s00429-013-0515-9

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