Regional differences in testosterone effects on vasopressin receptors and on vasopressin immunoreactivity in intact and castrated Siberian hamsters.

@article{DuboisDauphin1994RegionalDI,
  title={Regional differences in testosterone effects on vasopressin receptors and on vasopressin immunoreactivity in intact and castrated Siberian hamsters.},
  author={Michel L Dubois-Dauphin and J. M. Theler and A. Ouarour and Paul P{\'e}vet and Claude E Barberis and J. J. Dreifuss},
  journal={Brain research},
  year={1994},
  volume={638 1-2},
  pages={267-76}
}
Vasopressin binding sites were detected in the brain of the Siberian hamster, using [3H]vasopressin and a 125I-labelled linear vasopressin antagonist specific for V1 vasopressin receptors. In the ventromedial and premammillary nuclei, the density of the binding was lower in the females than in the males. The effect of castration and of testosterone replacement was assessed in males. Two distinct effects were observed. Orchidectomy diminished significantly the vasopressin binding in the… CONTINUE READING