Regional differences in resting extracellular potassium levels of rat brain

@article{Moghaddam1987RegionalDI,
  title={Regional differences in resting extracellular potassium levels of rat brain},
  author={Bita Moghaddam and Ralph Adams},
  journal={Brain Research},
  year={1987},
  volume={406},
  pages={337-340}
}
The extracellular potassium concentration in the cerebral cortex of the mammalian brain has been repeatedly reported to be approximately 3.0 mM. We have made detailed measurements with potassium-selective microelectrodes and have found significantly lower extracellular potassium concentrations in unstimulated rat brain caudate and thalamus (1.9-2.5 mM) when compared to cortex and cerebral spinal fluid (3.0-3.5 mM). These regional differences may be caused by variations in spontaneous activity… CONTINUE READING