Regional differences in normal and cancer-associated glycoconjugates of the human colon.

@article{Bresalier1985RegionalDI,
  title={Regional differences in normal and cancer-associated glycoconjugates of the human colon.},
  author={Robert S. Bresalier and Clement Richard Boland and Young Ju Kim},
  journal={Journal of the National Cancer Institute},
  year={1985},
  volume={75 2},
  pages={249-60}
}
Because inherent regional differences in colonic epithelium may determine the biologic behavior of tumors originating from different sites, and inasmuch as colonic epithelial cells secrete mucins that may reflect the state of cell differentiation, colonic goblet cell mucin was analyzed with the use of fluorescein isothiocyanate-conjugated lectins and fluorescence microscopy in normal fetal and adult mucosa and in cancers of the proximal and distal colon. In the adult proximal colon only the… CONTINUE READING
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