Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse

@article{Shum1996RegionalDI,
  title={Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse},
  author={Alisa S. W. Shum and Andrew J Copp},
  journal={Anatomy and Embryology},
  year={1996},
  volume={194},
  pages={65-73}
}
A study of neuroepithelial morphogenesis in the mouse embryo has identified three modes of neural tube formation that occur consecutively as neurulation progresses along the spinal region. The three modes of neurulation differ in the extent to which the neuroepithelium exhibits formation of ‘hinge points’, i.e. localised bending owing to reduction in apical surface area. In Mode 1, bending occurs only in the neuroepithelium overlying the notochord, creating a median hinge point. The neural… CONTINUE READING

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