Regional differences in incidence and patient characteristics of moyamoya disease: a systematic review

  title={Regional differences in incidence and patient characteristics of moyamoya disease: a systematic review},
  author={R Kleinloog and Luca Regli and G.J.E. Rinkel and Catharina J.M. Klijn},
  journal={Journal of Neurology, Neurosurgery \& Psychiatry},
  pages={531 - 536}
Background and purpose Moyamoya disease (MMD) is a rare cause of stroke, initially described in Japan. In other countries, incidences and presenting symptoms may differ from those in Japan. The literature on regional differences in incidence and patient characteristics of MMD was systematically reviewed. Methods Medline, EMBASE and CINAHL were searched for population based studies on MMD published between January 1969 and January 2011. From studies that met predefined inclusion criteria… 
Incidence and prevalence of moyamoya disease in urban China: a nationwide retrospective cohort study
The results confirm that MMD is relatively common in East Asians, but the rates in China were lower than those in other East Asian countries such as Japan and Korea, and revealed new sight into MMD.
Epidemiology of Moyamoya Disease in Taiwan: A Nationwide Population-Based Study
The incidence of moyamoya disease has increased in adults but not in children from 2000 to 2011 in Taiwan, and sex ratio and comorbid conditions differed by age and study period.
Moyamoya vasculopathy – Patient demographics and characteristics in the Finnish population
The results support in part the Western phenotype of the disease considering the later presentation and larger female predominance compared to the Asian moyamoya vasculopathy reports, but the proportion of ischemic strokes and hemorrhagic strokes is closer to Japanese population than German population.
Risk factors for postoperative stroke in adults patients with moyamoya disease: a systematic review with meta-analysis
This systematic review and meta-analysis indicated that preoperative ischemic events, PCA involvement and diabetes were independent risk factors for postoperative stroke in MMD patients and it is very necessary to detect these risk factors and prevent postoperative complications in time.
Clinical Characteristics and Natural History of Quasi-Moyamoya Disease.
  • Meng Zhao, Zhiqin Lin, Ji-zong Zhao
  • Medicine, Psychology
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
  • 2017
Coexisting diseases of moyamoya vasculopathy.


Epidemiological features of Moyamoya disease in Japan: findings from a nationwide survey
Epidemiological study of Moyamoya disease in Taiwan
Current state of study on moyamoya disease in Japan.
Prevalence and Clinicoepidemiological Features of Moyamoya Disease in Japan: Findings From a Nationwide Epidemiological Survey
The estimated prevalence of moyamoya disease in Japan has almost doubled during the recent decade and the clinicoepidemiological features of the patients in the present study were almost similar to those obtained in previous ones.
A survey of Moyamoya disease in Hawaii
Novel epidemiological features of moyamoya disease
The epidemiological features of moyamoya disease determined by this survey varied considerably from previous data: the detection rate and prevalence of the disease were higher than those reported previously, and the highest peak of onset age was older than those report previously.
Clinical features of moyamoya disease in the United States.
Observations indicate that moyamoya disease may have a different clinical expression in the United States than in Asia, and may demonstrate a trend toward a lower stroke recurrence rate and better functional outcome after synangiosis.
Epidemiological and clinical features of Moyamoya disease in Nanjing, China
Clinical Features and Outcome in North American Adults With Moyamoya Phenomenon
Moyamoya phenomenon in North American adults is associated with a high risk of recurrent stroke, particularly those with bilateral involvement and ischemic symptoms, and data suggest a potential benefit with surgery if diagnosis could be made earlier.
A Co-Operative Study: Clinical Characteristics of 334 Korean Patients with Moyamoya Disease Treated at Neurosurgical Institutes (1976–1994)
Treatment policies, including indications for bypass surgery and commonly used drugs, were somewhat different according to the institution, and overall favorable outcome was 73%, and the most significant factor affecting poor outcome was haemorrhagic manifestation.