Regional differences in cholinergic activity of muscle fibers from the human gastroesophageal junction.

@article{Preiksaitis1997RegionalDI,
  title={Regional differences in cholinergic activity of muscle fibers from the human gastroesophageal junction.},
  author={Harold G. Preiksaitis and Nicholas E. Diamant},
  journal={The American journal of physiology},
  year={1997},
  volume={272 6 Pt 1},
  pages={G1321-7}
}
Muscles of the gastroesophageal junction that contribute to the lower esophageal sphincter (LES) include clasplike semicircular fibers on the right and slinglike oblique gastric fibers on the left. This study examined whether in vitro differences between the sling and clasp muscles could account for the in vivo asymmetry of LES pressure and its cholinergic contribution. Isometric tension was recorded from muscle strips of the sling, clasp, and circular layers of the esophagus and gastric fundus… CONTINUE READING