Regional decreases in renal oxygenation during graded acute renal arterial stenosis: a case for renal ischemia.

@article{Warner2009RegionalDI,
  title={Regional decreases in renal oxygenation during graded acute renal arterial stenosis: a case for renal ischemia.},
  author={Lizette V. Warner and Sabas I Gomez and Rodney J. Bolterman and John A Haas and Michael Bentley and Lilach Orly Lerman and Juan Carlos Romero},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2009},
  volume={296 1},
  pages={R67-71}
}
Ischemic nephropathy describes progressive renal failure, defined by significantly reduced glomerular filtration rate, and may be due to renal artery stenosis (RAS), a narrowing of the renal artery. It is unclear whether ischemia is present during RAS since a decrease in renal blood flow (RBF), O(2) delivery, and O(2) consumption occurs. The present study tests the hypothesis that despite proportional changes in whole kidney O(2) delivery and consumption, acute progressive RAS leads to… CONTINUE READING

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