Regional control of chromatin organization by noncoding roX RNAs and the NURF remodeling complex in Drosophila melanogaster.

@article{Bai2007RegionalCO,
  title={Regional control of chromatin organization by noncoding roX RNAs and the NURF remodeling complex in Drosophila melanogaster.},
  author={Xianquan Bai and Erica Larschan and So Yeon Kwon and Paul Badenhorst and Mitzi I. Kuroda},
  journal={Genetics},
  year={2007},
  volume={176 3},
  pages={1491-9}
}
Dosage compensation in Drosophila is mediated by a histone-modifying complex that upregulates transcription of genes on the single male X chromosome. The male-specific lethal (MSL) complex contains at least five proteins and two noncoding roX (RNA on X) RNAs. The mechanism by which the MSL complex targets the X chromosome is not understood. Here we use a… CONTINUE READING