Regional cerebrovascular responses to progressive hypotension after traumatic brain injury in cats.

@article{Dewitt1992RegionalCR,
  title={Regional cerebrovascular responses to progressive hypotension after traumatic brain injury in cats.},
  author={Douglas S. Dewitt and Donald S. Prough and Christopher L. Taylor and Janet Whitley and Dwight D. Deal and S M Vines},
  journal={The American journal of physiology},
  year={1992},
  volume={263 4 Pt 2},
  pages={H1276-84}
}
We investigated the effects of hypotension on cerebral blood flow (CBF) after traumatic brain injury (TBI) in cats. Isoflurane-anesthetized cats were prepared for TBI and for microsphere measurements of total (T) and regional (r) CBF. Four groups were studied: sham injury (group I, n = 6); TBI (group II, n = 6); isoflurane anesthesia, no TBI or hypotension (group III, n = 4); and isoflurane and TBI, no hypotension (group IV, n = 8). After TBI or sham trauma, mean arterial pressure (MAP) was… CONTINUE READING

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