Regional cerebral metabolites, blood flow, plasma volume, and mean transit time in total cerebral ischemia in the rat.

@article{Crumrine1991RegionalCM,
  title={Regional cerebral metabolites, blood flow, plasma volume, and mean transit time in total cerebral ischemia in the rat.},
  author={R. Christian Crumrine and Joseph C. LaManna},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={1991},
  volume={11 2},
  pages={272-82}
}
Cerebral high-energy metabolites and metabolic end products were measured during and following total cerebral ischemia in the rat. During cerebral ischemia, lactate accumulation was greatest in the hippocampus, followed by the cerebral cortex and striatum. Following reperfusion, the rate of lactate clearance was slower in the hippocampus than in the other two regions. Regional CBF, cerebral plasma volume (CPV), and calculated mean transit time (MTT) were determined following reflow of ischemic… CONTINUE READING

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