Regional cerebral blood flow changes associated with clitorally induced orgasm in healthy women

@article{Georgiadis2006RegionalCB,
  title={Regional cerebral blood flow changes associated with clitorally induced orgasm in healthy women},
  author={Janniko R. Georgiadis and Rudie Kortekaas and Rutger Kuipers and Arie Nieuwenburg and Jan Pruim and Antje A. Reinders and Gert Holstege},
  journal={European Journal of Neuroscience},
  year={2006},
  volume={24}
}
There is a severe lack of knowledge regarding the brain regions involved in human sexual performance in general, and female orgasm in particular. We used [15O]‐H2O positron emission tomography to measure regional cerebral blood flow (rCBF) in 12 healthy women during a nonsexual resting state, clitorally induced orgasm, sexual clitoral stimulation (sexual arousal control) and imitation of orgasm (motor output control). Extracerebral markers of sexual performance and orgasm were rectal pressure… Expand

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  • J. Georgiadis
  • Psychology, Medicine
  • Socioaffective neuroscience & psychology
  • 2012
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References

SHOWING 1-10 OF 77 REFERENCES
Brain Activation during Human Male Ejaculation
TLDR
Insight is provided into which regions in the human brain play a primary role in ejaculation, and the results might have important implications for understanding of how human ejaculation is brought about, and for the ability to improve sexual function and satisfaction in men. Expand
Human brain activation during sexual stimulation of the penis
TLDR
The concept that during sexual performance the salience of the stimulus, represented by activation of the insula and SII, is of greater significance than the exact location of the stimuli, encoded in SI, is put forward. Expand
Neuroanatomical Correlates of Visually Evoked Sexual Arousal in Human Males
TLDR
PET identified brain regions whose activation was correlated with visually evoked sexual arousal in males, and activation of some of these areas was positively correlated with plasma testosterone levels. Expand
Brain processing of visual sexual stimuli in human males
TLDR
A model of the brain processes mediating the cognitive, emotional, motivational, and autonomic components of human male sexual arousal is proposed. Expand
Brain processing of visual sexual stimuli in men with hypoactive sexual desire disorder
TLDR
Patients with HSDD brain regions where functional perturbations disrupt the regulation of sexual motivation are identified, including those areas of the anterior cingulate gyrus and of the frontal lobes that are involved in premotor processes. Expand
Brain activation and sexual arousal in healthy, heterosexual males.
TLDR
This study demonstrates the feasibility of examining brain activation/sexual response relationships in an fMRI environment and reveals a number of brain structures whose activation is time-locked to sexual arousal. Expand
Cerebral Activation Associated with Sexual Arousal in Response to a Pornographic Clip: A 15O–H2O PET Study in Heterosexual Men
TLDR
Sexual arousal was mainly associated with activation of bilateral, predominantly right, inferoposterior extrastriate cortices, of the right inferolateral prefrontal cortex and of the midbrain, and that was discussed in the light of current theories concerning selective attention, "mind reading" and mirroring, reinforcement of pleasurable stimuli, and penile erection. Expand
Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI
TLDR
Light is shed on the psychophysiology of male sexuality and new perspectives for the diagnosis, therapy, and possible rehabilitation of sexual dysfunction are opened by fMRI images that highlighted a complex neural circuit involved in sexual arousal. Expand
Brain activation patterns during video sexual stimulation following the administration of apomorphine: results of a placebo-controlled study.
TLDR
Apomorphine significantly enhances the activation of cortical and subcortical brain function during video sexual stimulation and may have an underlying functional abnormality of the brain acting as a previously unrecognised aetiological factor. Expand
A PET study on cortical and subcortical control of pelvic floor musculature in women
TLDR
The results revealed that the superomedial precentral gyrus, the most medial portion of the motor cortex, is activated during pelvic floor contraction and the superolateral pre central gyrus during contraction of the abdominal musculature. Expand
...
1
2
3
4
5
...