Regional cerebral blood flow and glucose utilization during hypothermia in newborn dogs.

@article{Palmer1989RegionalCB,
  title={Regional cerebral blood flow and glucose utilization during hypothermia in newborn dogs.},
  author={Charles Palmer and Robert C. Vannucci and Melanie A Christensen and Robert M. Brucklacher},
  journal={Anesthesiology},
  year={1989},
  volume={71 5},
  pages={730-7}
}
To ascertain the effect of profound hypothermia on brain function and metabolism, newborn dogs were subjected to surface cooling during which regional cerebral blood flow (rCBF) and glucose utilization (rCGU) were measured with iodo-[14C]-antipyrine and 2-deoxy-[14C]-glucose, respectively. Puppies were anesthetized with nitrous oxide, paralyzed, and their lungs artificially ventilated to maintain arterial normoxia (PaO2 greater than 60 mmHg) and normal acid-base balance (PaCO2 = 35-41 mmHg; pHa… CONTINUE READING